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Source: http://www.architecturalmailboxes.com/blog/2013/03/architectural-mailboxes-are-on-houzz-com/
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The field of regenerative medicine holds great promise, propelled by greater understanding of how stem cells differentiate themselves into many of the body's different cell types. But clinical applications in the field have been slow to materialize, partially owing to difficulties in replicating the conditions these cells naturally experience.
A team of researchers from the University of Pennsylvania has generated new insight on how a stem cell's environment influences what type of cell a stem cell will become. They have shown that whether human mesenchymal stem cells turn into fat or bone cells depends partially on how well they can "grip" the material they are growing in.
The research was conducted by graduate student Sudhir Khetan and associate professor Jason Burdick, along with professor Christopher Chen, all of the School of Engineering and Applied Science's Department of Bioengineering. Others involved in the study include Murat Guvendiren, Wesley Legant and Daniel Cohen.
Their study was published in the journal Nature Materials.
Much research has been done on how stem cells grow on two-dimensional substrates, but comparatively little work has been done in three dimensions. Three-dimensional environments, or matrices, for stems cells have mostly been treated as simple scaffolding, rather than as a signal that influences the cells' development.
Burdick and his colleagues were interested in how these three-dimensional matrices impact mechanotransduction, which is how the cell takes information about its physical environment and translates that to chemical signaling.
"We're trying to understand how material signals can dictate stem cell response," Burdick said. "Rather than considering the material as an inert structure, it's really guiding stem cell fate and differentiation ? what kind of cells they will turn into."
The mesenchymal stem cells the researchers studied are found in bone marrow and can develop into several cell types: osteoblasts, which are found in bone; chondrocytes, which are found in cartilage; and adipocytes, which are found in fat.
The researchers cultured them in water-swollen polymer networks known as hydrogels, which share some similarities with the environments stem cells naturally grow in. These materials are generally soft and flexible ? contact lenses, for example, are a type of hydrogel ? but can vary in density and stiffness depending on the type and quantity of the bonds between the polymers. In this case, the researchers used covalently cross-linked gels, which contain irreversible chemical bonds.
When seeded on top of two-dimensional covalently cross-linked gels, mesenchymal stem cells spread and pulled on the material differently depending on how stiff it was. Critically, the mechanics guide cell fate, or the type of cells they differentiate it into. A softer environment would produce more fat-like cells and a stiffer environment, where the cells can pull on the gel harder, would produce more bone-like cells.
However, when the researchers put mesenchymal stem cells inside three-dimensional hydrogels of varying stiffness, they didn't see these kinds of changes.
"In most covalently cross-linked gels, the cells can't spread into the matrix because they can't degrade the bonds ? they all become fat cells," Burdick said. "That tells us that in 3D covalent gels the cells don't translate the mechanical information the same way they do in a 2D system."
To test this, the researchers changed the chemistry of their hydrogels so that the polymer chains were connected by a peptide that the cells could naturally degrade. They hypothesized that, as the cells spread, they would be able to get a better grip on their surrounding environment and thus be more likely to turn into bone-like cells.
In order to determine how well the cells were pulling on their environment, the researchers used a technique developed by Chen's lab called 3D traction force microscopy. This technique involves seeding the gel with microscopic beads, then tracking their location before and after a cell is removed.
"Because the gel is elastic and will relax back into its original position when you remove the cells," Chen said, "you can quantify how much the cells are pulling on the gel based on how much and which way it springs back after the cell is removed."
The results showed that the stem cells' differentiation into bone-like cells was aided by their ability to better anchor themselves into the growth environment.
"With our original experiment, we observed that the cells essentially didn't pull on the gel. They adhered to it and were viable, but we did not see bead displacement. They couldn't get a grip," Burdick said. "When we put the cells into a gel where they could degrade the bonds, we saw them spread into the matrix and deform it, displacing the beads."
As an additional test, the researchers synthesized another hydrogel. This one had the same covalent bonds that the stem cells could naturally degrade and spread through but also another type of bond that could form when exposed to light. They let the stem cells spread as before, but at the point the cells would begin to differentiate ? about a week after they were first encapsulated ? the researchers further "set" the gel by exposing it to light, forming new bonds the cells couldn't degrade.
"When we introduced these cross-links so they could no longer degrade the matrix, we saw an increase toward fat-like cells, even after letting them spread," Burdick said. "This further supports the idea that continuous degradation is needed for the cells to sense the material properties of their environment and transduce that into differentiation signals."
Burdick and his colleagues see these results as helping develop a better fundamental understanding of how to engineer tissues using stem cells.
"This is a model system for showing how the microenvironment can influence the fate of the cells," Burdick said.
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University of Pennsylvania: http://www.upenn.edu/pennnews
Thanks to University of Pennsylvania for this article.
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Source: http://www.labspaces.net/127524/Researchers_show_stem_cell_fate_depends_on__grip__
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By Martyn Herman LONDON, March 28 (Reuters) - Whether by design, necessity, self-interest or because of all three, nurturing youngsters has become fashionable for England's elite with no expense spared in the hunt for the new Wayne Rooney or Steven Gerrard. The length and breadth of the country, scouts from top clubs are hoovering up promising footballers barely old enough to tie their bootlaces in a bid to unearth the 30 million pounds ($45.40 million) treasures of the future. ...
Source: http://news.yahoo.com/now-lets-balki-bartokomous-weather-203148628.html
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Source: http://the-gadgeteer.com/2013/03/29/the-tactical-pen-a-pen-james-bond-would-want/
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The push and pull between the Republican Party's members who are more and less enlightened on matters of race has been going on for a long time. And in just the last decade, the GOP has seen plenty of two-steps-forward-three-steps-back moments when it's tried to minority outreach programs. Take Ronald Reagan. In 1977, shortly before Jimmy Carter was sworn in, he spoke of a "New Republican party" and said it's "still going to be the party of Lincoln and that means we are going to have to come to grips with what I consider to be a major failing of the party: its failure to attract the majority of black voters." Three years later when he was running against President Carter, he didn't reply to an NAACP invitation to address their annual gathering, but showed up the next year after he was sworn and compared welfare programs to slavery, saying "'Just as the Emancipation Proclamation freed black people 118 years ago, today we need to declare an economic emancipation" and asked the attendees "to join me to build a coalition for change." The reception was cool, but he at least he received a hug from NAACP president Margaret Bush Wilson after his speech.?
RELATED: Conservatives Worry Latinos Aren't Worth Pandering To
35 years after Reagan pondered a G.O.P. presidential defeat, the ?Republican National Committee's "autopsy" of the 2012 election promises to really-for-real-this-time reach out to people who aren't "stuffy old men" (its own words!),?Republicans didn't wake up the day after the election and realized they needed to make the party less white. But, as in the past, the very public proclamations about being a more welcoming organization has thrown a harsher light on the party members who are anything but. Take, for instance, Alaska Rep. Don Young has to?apologize?for using the slur "wetbacks" on a radio show Thursday. "I know that this term is not used in the same way nowadays," Young said, "and I meant no disrespect." ?
RELATED: Karl Rove's History of Bad Advice Is Haunting the GOP
He's wrong in more than one respect. The word has not changed. It's just as offensive today as it was in 1920 to refer to Mexican migrant laborers being welcomed into Texas by business leaders?and as it was in 1954 when a mass deportation of those Mexican migrants was officially dubbed Operation Wetback. What has changed is the country and the acceptability of casual racism and the ?GOP has struggled to show it understands how much things have changed.?An ex-RNC field staffer told?BuzzFeed's McKay Coppins that "whenever they were notified of a new Republican outreach effort, they would pass around a Beanie Baby ? which they had dubbed the 'pander bear' ? and make fun of the 'tokenism.'" It's not that they were racist or something, the ex-staffer said, they just didn't see the point.
RELATED: Latino Votes Could Be Casualty of Romney-Perry Sparring
Any why should they? These sorts of political initiatives have come and gone before. Here's just a sampling.
RELATED: Marco Rubio Still Can't Slip Away from Obama on Immigration
2004: Minorities will love Republicans' social values.
RELATED: Chicago's Gun Dilemma, What Boeing Knew, and a Bloomberg Musical
Republicans tried to appeal to blacks and Latinos based on "family values" -- like opposition to abortion and gay marriage. George W. Bush's reelection campaign pushed for an anti-gay marriage constitutional amendment in Ohio to turn out voters, and Bush got 16 percent of black voters?in 2004 -- more than double the 7 percent got in 2000. Bush's faith-based initiatives office held supposedly non-partisan conferences with religious leaders to talk about poverty in their communities, and black religious clergy were specifically targeted.
But Republicans can't duplicate that today -- and probably wouldn't want to. After President Obama endorsed gay marriage, black voters' support for it climbed to 59 percent. And, as the RNC's autopsy noted, young voters support gay marriage even more. Even if Republicans could still lure minorities by opposing gay rights, it would cost them with young people.
2005: Black people should support privatizing Social Security because they'll die sooner.
Yes, in 2005, Bush's White House thought telling black people they would die sooner than white people would be a really good way to sell conservative fiscal policy -- instead of, say, make black people wonder what Republicans were suggesting to fix that problem. The?Los Angeles Times reported in March 2005:
The most provocative element of the GOP message to African Americans: Their shorter life expectancy means Social Security is not a favorable deal for them, a point contested by Bush's critics.
The president's plan for private accounts, Republicans say, would particularly benefit African Americans by allowing them to build wealth more rapidly and pass a portion of their Social Security contributions to their heirs.
That story noted a persistant problem for Republicans, which you can see in black voters' growing support for gay marriage after Obama's endorsement: when black voters find out they like a policy supported by Republicans, they don't like the party more, they like the policy less. In polling on Social Security privatization, the Los Angeles Times wrote,?"Support for the concept plummets when the survey questions link private accounts to Bush or another Republican."
2007: Immigration reform and more Latino GOP faces will make Latinos like the party more.
Though Bush had gotten record levels of support (40 percent) from Latino voters, in the 2006 election, they swung back to the Democrats. According to exit polls, about 70 percent of Latinos voted for Democrats in the midterm elections. Polls showed they cared more about the Iraq war than immigration, but the immigration debate among Republicans had already gotten ugly. In 2007, it got worse.
After the 2006 elections, the GOP tried to do what the RNC is trying to do in 2013: Promote more black and Latino Republicans to prominent positions. Bush picked the next chair of the RNC to be Florida Sen. Mel Martinez, a Cuban immigrant who favored a path to citizenship for illegal immigrants. Conservatives revolted.?Colorado Rep. Tom Tancredo warned that Martinez would fail if he?"rejects the will of rank-and-file Republicans and uses the position to advocate for things like the president's amnesty proposal, then I believe the party could be headed for another shellacking at the polls in 2008."?Immigration reform died in Congress.?Tancredo would go on to run for president as the anti-immigration candidate. Republicans got shellacked in 2008, but not for the reason Tancredo predicted. Though RNC chair is a two-year position, Martinez stepped down in October 2007. At the time, the RNC's Latino outreach chair still hadn't been filled. At the time, the?Republican National Hispanic Assembly had no office and had considered closing,?Newsweek reported.
Glimmers of hope turned out to be false ones. Check out this fateful closing paragraph from?Newsweek?in September 2007 about whether Republicans could repair the damage following the immigration fight:
Already, two of the GOP candidates earn more favorable marks than their Republican peers among Latino politicos: Mitt Romney, who's got an energetic outreach effort led by Al Cardenas, the former chair of the Florida Republican Party; and McCain, who championed immigration reform in the Senate. It will be up to them to undo any damage their party has done.
Romney, of course, did not do that. He lost in 2008. In 2012, he said in Republican primary debates that he favored self-deportation -- making life for immigrants so horrible they go home on their own. When Rick Perry accused him of employing illegal immigrants, Romney famously said, "I?m running for office, for Pete?s sake, I can?t have illegals."
Republicans' latest outreach effort shouldn't be seen as a change of heart, but part of a long, hard slog fighting the Don Youngs of the party -- and the temptations to pander to them.
Source: http://news.yahoo.com/gop-tried-failed-minority-outreach-many-times-172024728.html
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By Jeffrey Kopman
According to a new Harris Poll survey, conducted on behalf of the management consulting firm Accenture, less than one-third of U.S. doctors think patients should have full access to their own electronic health records.
As a patient, you may literally trust your doctor with your life, and the doctor-patient relationship relies on this level of trust. The relationship should be one of give and take, even if the exchange is sometimes dominated by the professional.
So it may come as a surprise that 65 percent of docs believe their patients should have only limited access to their electronic health records, and 4 percent believe patients should have no access at all.
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One thing is clear ? patients believe electronic medical records improve their care. According to a 2011 survey, conducted by GfK Roper on behalf of Practice Fusion, a San Francisco-based electronic health record provider, 78 percent of patients whose doctors kept electronic medical records felt that their care improved.
"Patients want their healthcare to reflect the fact we're in the 21st century," said Ryan Howard, CEO of Practice Fusion. "They want to have prescriptions sent electronically, to receive email appointment reminders and to review past diagnoses and upcoming appointments online."
?Several US health systems have proven that the benefits outweigh the risks in allowing patients open access to their medical records, and we expect this trend to continue,? said Mark Knicrehm, senior global managing director of Accenture Health, of the poll?s results.
While a majority of doctors in the Accenture survey wouldn?t trust patients with full access to their records, 81 percent said they wanted their patients to keep the records up to date, which may seem like a disconnect.
Primarily, though, the doctors are referring to updating personal information, not medical information. Almost all doctors polled think patients should update their own demographic information (95 percent), family history (88 percent), medications (86 percent), allergies (85 percent), and even some medical information, like new symptoms and self-administered test results (81 percent).
There seem to be few disadvantages to giving patients access to records and some real advantages, according to experts and commentators. So why do many doctors feel that their patients should not have full access to their electronic medical records?
Stephen Baker, author of The Numerati blog, wrote that patient sensitivity may be to blame for doctors' unwillingness to share medical records.
?This would not be a problem if we, as a society, weren't so hypersensitive to 'hurtful' words, and eager to sue in cases of errors,? Baker stated on his blog.
He used an example of a doctor speculating about his or her patient being the victim of abuse. While the patient might be offended on reading this information in their electronic medical record, the doctor might feel that it's important to document their observations. Baker concluded, ?if we want the data, we should be ready to see and accept it, even when offensive. This openness would pay off richly.?
Thomas J. Vento, MD, a family doctor in private practice in Reisterstown, Md., sees the benefits of open access to medical records, because patients can help prevent medical errors.
"It?s a great idea to give your family doctor a copy to keep in his file, but it?s also very important to have your own copy of the health journal in case of a medical emergency," Dr. Vento said. "Being an active voice in health care is an integral part of getting the best care you can for yourself and your children."
After a 2012 study found that doctors failed to read many test results when patients were discharged from hospitals, experts claimed that electronic records could help "prevent important information from falling through cracks."
"[This] problem could be solved with electronic medical records that keep track of test results and alert doctors when the results have not been reviewed," said Gordon Schiff, MD, associate director of the Brigham Center for Patient Safety Research and Practice, at the time. "Patients also can play a role by keeping track of their tests and asking their doctor about the results."
As doctors and medical institutions continue to switch to electronic medical records, and patients demand more access, the debate will continue: How much information should patients have access to?
"Electronic Health Records: Doctors Want to Keep Patients Out" originally appeared on Everyday Health.
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By David Chance and Phil Stewart
SEOUL/WASHINGTON (Reuters) - North Korea put its missile units on standby on Friday to attack U.S. military bases in South Korea and the Pacific, after the United States flew two nuclear-capable stealth bombers over the Korean peninsula in a rare show of force.
North Korean leader Kim Jong-un signed off on the order at a midnight meeting of top generals and "judged the time has come to settle accounts with the U.S. imperialists in view of the prevailing situation", the official KCNA news agency said.
The North has an arsenal of Soviet-era short-range Scud missiles that can hit South Korea and have been proven, but its longer-range Nodong and Musudan missiles that could in theory hit U.S. Pacific bases are untested.
On Thursday, the United States flew two radar-evading B-2 Spirit bombers on practice runs over South Korea, responding to a series of North Korean threats. They flew from the United States and back in what appeared to be the first exercise of its kind, designed to show America's ability to conduct long-range, precision strikes "quickly and at will", the U.S. military said.
The news of Kim's response was unusually swift.
"He finally signed the plan on technical preparations of strategic rockets of the KPA (Korean People's Army), ordering them to be on standby for fire so that they may strike any time the U.S. mainland, its military bases in the operational theaters in the Pacific, including Hawaii and Guam, and those in South Korea," KCNA said.
South Korea's Yonhap news agency reported there had been additional troop and vehicle movements at the North's mid- and long-range missile sites, indicating they may be ready to fire.
"Sharply increased movements of vehicles and soldiers have been detected recently at North Korea's mid and long-range missile sites," Yonhap quoted a South Korean military source as saying.
It was impossible to verify the report which did not specify a time frame, although South Korea's Defense Ministry said on Friday that it was watching shorter-range Scud missile sites closes as well as Nodong and Musudan missile batteries.
The North has launched a daily barrage of threats since early this month when the United States and the South, allies in the 1950-53 Korean War, began routine military drills.
The South and the United States have said the drills are purely defensive in nature and that no incident has taken place in the decades they have been conducted in various forms.
The United States also flew B-52 bombers over South Korea earlier this week.
The North has put its military on highest readiness to fight what it says are hostile forces conducting war drills. Its young leader has previously given "final orders" for its military to wage revolutionary war with the South.
ECONOMIC ZONE
Despite the tide of hostile rhetoric from Pyongyang, it has kept open a joint economic zone with the South which generates $2 billion a year in trade, money the impoverished state can ill-afford to lose.
Pyongyang has also canceled an armistice agreement with the United States that ended the Korean War and cut all communications hotlines with U.S. forces, the United Nations and South Korea.
"The North Koreans have to understand that what they're doing is very dangerous," U.S. Defense Secretary Chuck Hagel told reporters at the Pentagon on Thursday.
"We must make clear that these provocations by the North are taken by us very seriously and we'll respond to that."
The U.S. military said that its B-2 bombers had flown more than 6,500 miles to stage a trial bombing raid from their bases in Missouri as part of the Foal Eagle war drills being held with South Korea.
The bombers dropped inert munitions on the Jik Do Range, in South Korea, and then returned to the continental United States in a single, continuous mission, the military said.
Thursday's drill was the first time B-2s flew round-trip from the mainland United States over South Korea and dropped inert munitions, a Pentagon spokeswoman said.
Victor Cha, a North Korea expert at the Center for Strategic and International Studies, said the drill fitted within the context of ramped-up efforts by the Pentagon to deter the North from acting upon any of its threats.
Asked whether he thought the latest moves could further aggravate tensions on the peninsula, Cha, a former White House official, said: "I don't think the situation can get any more aggravated than it already is."
South Korea denied suggestions on Friday that the bomber drills contained an implicit threat of attack on the North.
"There is no entity on the earth who will strike an attack on North Korea or expressed their wishes to do so," a spokesman for the South's Unification Ministry said.
Despite the shrill rhetoric from Pyongyang, few believe North Korea, formally known as the Democratic People's Republic of Korea, will risk starting a full-out war.
Still, Hagel, who on March 15 announced he was bolstering missile defenses over the growing North Korea threat, said all of the provocations by the North had to be taken seriously.
"Their very provocative actions and belligerent tone, it has ratcheted up the danger and we have to understand that reality," Hagel said, renewing a warning that the U.S. military was ready for "any eventuality" on the peninsula.
North Korea conducted a third nuclear weapons test in February in breach of U.N. sanctions and despite warnings from China, its one major diplomatic ally.
(Additional reporting by David Alexander in Washington; Editing by Warren Strobel, Paul Simao and Raju Gopalakrishnan)
Source: http://news.yahoo.com/north-korea-readies-rockets-u-flies-stealth-bombers-020309202.html
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TORONTO (AP) ? Research In Motion Ltd., once written off as dead amid fierce competition from more modern mobile devices such as the iPhone, surprised Wall Street Thursday by returning to profitability and shipping more BlackBerry 10 phones than expected in the most recent quarter.
It will take several quarters, though, to know whether RIM is on a path toward a successful turnaround. RIM just entered the crucial U.S. market with the new phone last week. And despite selling a million BlackBerry 10 phones in other countries, RIM lost subscribers for the second consecutive quarter.
Thursday's earnings report provided a first glimpse of how the BlackBerry 10 system, widely seen as crucial to the company's future, is selling internationally and in Canada since its debut Jan. 31. The 1 million new touch-screen BlackBerry Z10 phones were above the 915,000 that analysts had been expecting for the quarter that ended March 2. Details on U.S. sales are not part of the fiscal fourth quarter's financial results because the Z10 wasn't available there after the quarter ended.
Investors appeared mostly happy with the financial results. RIM's stock rose as high as $15.55 as trading opened Thursday after the release of results, though it saw a sharp drop in the final hour of trading and closed at $14.45, down 12 cents.
Many analysts had written RIM off last year, but now believe the Canadian company has a future.
"I thought they were dead. This is a huge turnaround," Jefferies analyst Peter Misek said from New York.
Misek said the Canadian company "demolished" the numbers, especially its gross margins. RIM reported gross margins of 40 percent, up from 34 percent a year earlier. The company credited higher average selling prices and higher margins for devices.
"This is a really, really good result," Misek said. "It's off to a good start."
The new BlackBerry 10 phones are redesigned for the new multimedia, Internet browsing and apps experience that customers are now demanding.
The BlackBerry, pioneered in 1999, had been the dominant smartphone for on-the-go business people and other consumers before the iPhone debuted in 2007 and showed that phones can handle much more than email and phone calls. RIM faced numerous delays modernizing its operating system with the BlackBerry 10. During that time, it had to cut more than 5,000 jobs and saw shareholder wealth decline by more than $70 billion.
In the most recent quarter, RIM earned $98 million, or 19 cents a share, compared with a loss of $125 million, or 24 cents a share, a year earlier. After adjusting for restructuring and other one-time items, RIM earned 22 cents a share. Analysts surveyed by FactSet had been expecting a loss of 31 cents.
Revenue fell 36 percent to $2.7 billion, from $4.2 billion. Analysts had expected $2.82 billion.
RIM shipped 6 million BlackBerry devices, including 1 million on the new system. But RIM lost about 3 million subscribers to end the quarter with 76 million. It's the second consecutive quarterly decline for RIM, whose subscriber based peaked at 80 million last summer.
Bill Kreyer, a tech analyst for Edward Jones, called the decline "pretty alarming."
"This is going to take a couple of quarters to really see how they are doing," Kreyer said.
The company also announced that co-founder Mike Lazaridis will leave the company. He and Jim Balsillie had stepped down as co-CEOs in January 2012 after several quarters of disappointing results, but Lazaridis said he stayed on as vice chairman and a board director to help new CEO Thorsten Heins and his team with the launch of the BlackBerry 10. With that underway, Lazaridis plans to retire May 1. He said he has no plans to sell his 5.7 percent stake in the company.
In an interview with The Associated Press, Lazaridis said the board wanted both him and Jim to stay, but Lazaridis decided "it was the right time" to leave.
Heins, formerly RIM's chief operating officer, has spent the past year cutting costs and steering the company toward the launch of new BlackBerry 10 phones. Lazaridis said Heins has done an excellent job completing the BlackBerry 10 system and launching it around the world.
"The results speak for themselves," Lazaridis said.
Sterne Agee analyst Shaw Wu said RIM returned to profitability much sooner than expected. He said it was driven by higher gross margins, cost reductions and the sale of the new BlackBerry.
In a research note, Wu wrote that RIM "is here to stay with stabilization in its business and balance sheet" but said the key question remains whether the company can maintain momentum in an industry dominated by Apple and Google's Android software.
The Z10 has received favorable reviews since its release, but the launch in the critical U.S. market was delayed until late this month as wireless carriers completed their testing.
A version with a physical keyboard, called the Q10, won't be released in the U.S. for two or three more months. The delay in selling the Q10 complicates RIM's efforts to hang on to customers tempted by the iPhone and a range of devices running Android. Even as the BlackBerry has fallen behind rivals in recent years, many users have stayed loyal because they prefer a physical keyboard over the touch screen on the iPhone and most Android devices.
RIM, which is changing is formal name to BlackBerry, said it expects to break even in the current quarter despite increasing spending on marketing by 50 percent compared with the previous quarter.
"To say it was a very challenging environment to deliver improved financial results could well be the understatement of the year," Heins said during a conference call with analysts.
Heins said more than half of the people buying the touch-screen Z10 were switching from rival systems. The company didn't provide details or specify whether those other systems were all smartphones. He said the Q10 will sell well among the existing BlackBerry user base. It's expected in some markets in April, but not in the U.S. until May or June.
Source: http://news.yahoo.com/rim-success-4q-too-early-declare-win-175330023--finance.html
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By Jason Szep SIT KWIN, Myanmar (Reuters) - The Muslims of Sit Kwin were always a small group who numbered no more than 100 of the village's 2,000 people. But as sectarian violence led by Buddhist mobs spreads across central Myanmar, they and many other Muslims are disappearing. Their homes, shops and mosques destroyed, some end up in refugee camps or hide in the homes of friends or relatives. Dozens have been killed. ...
Source: http://news.yahoo.com/google-augmented-reality-game-inspires-players-duel-one-020647537.html
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By Vernell Hackett
NASHVILLE, Tennessee (Reuters) - Country music singer Blake Shelton has never been one to shy away from his feelings, so when it came to recording his new album he sought out songs that reflected his current state of mind.
Life, he says, is "pretty awesome."
"It's all where I am in my life right now. I'm very content with my life. I'll be happy if it stays like this for a long time," Shelton, 36, told Reuters of his new album "Based on a True Story..."
After some 10 years in country music, Shelton's popularity has surged in his two years as a judge on NBC's "The Voice" singing contest, which is seen by about 13 million U.S. viewers a week.
The new album's first single, "Sure Be Cool If You Did," released in January, has already topped the U.S. country chart. "Based on a True Story...," released to coincide with the return of "The Voice" this week, is expected to debut near the top of next week's album chart.
"I didn't want to do any sad songs, damn it, but this is a country album so you have to do a couple," said Shelton.
"I had those years where I made those kinds of records and something will happen one of these days and it will be a part of my music again. But right now everything is pretty awesome," he added.
Shelton, 36, is the latest country star to break into the mainstream. His 2011 album "Red River Blue," reached No. 1 on the Billboard 200, buoyed in part by the singer's laid-back, fun-loving role on the TV show.
On the new album, Shelton, who forms a country music power couple with singer-wife Miranda Lambert, sings about tried-and-true country themes, including good ol' boys, picking up girls, being in love, losing the love of his life and bad jobs.
"The album is the story of my life from start to finish and I thought 'That's what we should call it because it is based on a true story,'" Shelton said.
The singer, who won the Country Music Association's Entertainer of the Year in 2012, said he wants people to get to know his personality through his music and "The Voice."
"I guess if doing what I did got me that award, I better keep being that guy," said Shelton, whose biggest hits include 2009's "Hillbilly Bone" and 2004's "Some Beach."
Shelton has emerged as the face of the country music industry on "The Voice," in which he and three other judges compete with each other to mentor rising singers and help them win a record deal.
"I've always felt a responsibility to make sure that every step along the way is a good one for our industry," he said. "I'm proud to be that person on 'The Voice' that represents country music."
Shelton will be back in the country music spotlight on April 7 as host for the third consecutive year of the Academy of Country Music Awards in Las Vegas.
(Reporting by Vernell Hackett, editing by Eric Kelsey, Jill Serjeant and Jackie Frank)
Source: http://news.yahoo.com/album-nbcs-voice-awesome-times-blake-shelton-163427960--finance.html
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From a timing perspective, it became much more attractive for Hotels to feel like they could get away with these fees when the arilines started in earnest with the ala carte fees for bags, choosing seats, etc. on top of the rates.
Personally as a consumer, I would prefer these businesses just give me one figure, with all taxes, "Resort Fees", "Energy Fees", etc. when I make a reservation. Who do they think they're fooling? Is the general public that stupid???
Source: http://www.vimovingcenter.com/talk/read.php?4,200448,200448
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RALEIGH, N.C. (AP) ? North Carolina Sen. Kay Hagan said Wednesday she backs marriage rights for same-sex couples, joining a growing number of Democratic Party politicians ahead of her re-election race next year.
Hagan announced her position as the U.S. Supreme Court heard oral arguments on the federal Defense of Marriage Act, a law that denies federal benefits to married same-sex couples.
"Marriage equality is a complex issue with strong feelings on both sides, and I have a great deal of respect for varying opinions on the issue," Hagan said on her official Facebook account. "After much thought and prayer, I have come to my own personal conclusion that we shouldn't tell people who they can love or who they can marry."
Hagan last year opposed a state constitutional amendment to ban gay marriage, saying it could make it more difficult for companies to recruit talent. President Barack Obama announced his support for the unions the day after 61 percent of North Carolina voters backed the gay-marriage amendment last May.
The amendment reflected North Carolina's urban-rural divide on social issues. The question passed in 92 of North Carolina's 100 counties, while the counties surrounding Raleigh, Chapel Hill, Durham and Charlotte among those where the question was defeated.
Hagan's position puts her in step with fellow Democrats like U.S. Sens. Jon Tester of Montana, Claire McCaskill of Missouri, and Mark Warner of Virginia, all of whom this week declared support for gay marriage. Republican Sen. Rob Portman of Ohio took that step last week.
But Hagan's statement carries political risks. She was elected in 2008 on the day that Obama won North Carolina by just 14,000 votes, marking the first victory for a Democratic presidential nominee since 1976. But North Carolina was the only battleground state Obama lost last year to Mitt Romney on the way to re-election.
An Election Day exit poll of voters conducted for The Associated Press in November found that just one-third of voters said they supported same-sex marriage.
Hagan said she believes religious institutions should not have to conduct same-sex marriages if that is inconsistent with their religious beliefs.
"But I think as a civil institution, this issue's time has come and we need to move forward," Hagan said. "The fabric of North Carolina and what makes our state so special is our families and our common desire for a brighter future for our children. No matter what your family looks like, we all want the same thing for our families - happiness, health, prosperity, a bright future for our children and grandchildren."
___
Emery Dalesio can be reached at http://twitter.com/emerydalesio.
Source: http://news.yahoo.com/us-sen-hagan-nc-backs-same-sex-marriage-165156223--election.html
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We're not as daring as Magellan (who died) or Columbus (who went crazy) or Henry Hudson (who froze), but in our dainty little way, we take astonishing risks. Well, maybe not astonishing. Maybe just embarrassing.
Some of the best science reporters, like the best Vaudevillians, the best circus performers, the best teachers, are hungry for attention ? not for themselves (well, maybe a little), but for a way to seize your mind, to bring you to an idea, a creature, a puzzle. We are a strange bunch, shy, desperate, ferocious ? we want you to know what we know, meet who we've met.
Here's a perfect example. I've got this friend, Destin, who is not even a fully-employed science reporter (though he's about to be). By day, he tests rockets for the U.S. Defense Department in Huntsville, Ala., but the rest of the time he explores physics, biology and explodes things, blowing up anything and everything (while, of course, wearing safety glasses ? because, as I said, we may look crazy, but we're dainty on the inside). He does his reporting on his own YouTube channel, called Smarter Every Day. He's his own cameraman, reporter, narrator, money-raiser and nuisance to his long-suffering wife.
Doing What Must Be Done
Recently, he took himself on a trip to the Amazon rainforest, accompanied by a gang of, you should excuse the expression, "frat boy" types (scientists, I suppose), who took him to a hole, literally a hole in a mound of mud or dirt deep in the forest. In that hole, they knew, was a tailless whip scorpion, a big, scary, frightening-looking multi-legged beast who is clearly, VERY CLEARLY, making Destin extremely uncomfortable. Lots of people get the creeps near spiders, which is what these are (though six-legged, they've got two more limbs up front, making them "amblypygids," part of the spider family). But true to our code (Explore, Describe, Pee in Your Pants) Destin has his Encounter. Yes, his eyes are squinched shut, and he's barely breathing, but he's a Science Reporter, Doing What Must Be Done ... as you will see ... right here ...
By the way, (and this is why we don't belong with Columbus, Magellan or Henry Hudson), according to the scientists at The Wild Classroom, tailless whip scorpions "are completely harmless. They have no way of inflicting stings, or in any way hurting a human being. [They] do not have venom, and their formidable pedipalps [those claw-like limbs] are used solely for capturing small prey like tiny crickets crawling on tree trunks."
They don't even have tails. Tailless scorpions are like mouthless dragons. Very un-dangerous. Their Latin name, "amblypigid," means "blunt rump." So Destin was never in harm's way, not even slightly.
The Science Reporting Difference ...
But this is why we are different from those other show folks who make fiction TV and movies ? we show you the truth. Destin may be a coward, but he knows the animal is not his enemy. Heck, he even takes it home to its hole after their "date."
They didn't do that in the Harry Potter movies. Harry Potter and the Goblet of Fire, features a tailless whip scorpion. Professor Mad-Eye Moody (the one with the magical eye) calls it "lethal" (hah!) and proceeds to torture the little guy until Hermione begs him to stop.
Dr. Moody may be a full professor at Hogwarts ? but he's no science reporter. We may not be pure-bred wizards, but we're made of truer stuff.
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Ramil Sitdikov / AFP - Getty Images
NASA astronaut Christopher Cassidy gets his spacesuit checked prior to Thursday's launch to the International Space Station. Straps bind Cassidy's knees close to his chest, in the position he'll have to maintain during most of the six-hour trip.
By James Oberg, NBC News Space Analyst
The speedier ride that three spacefliers are taking into orbit on Thursday will get them aboard the roomy International Space Station a lot sooner than on previous Soyuz space missions. It will lower the demand on expensive support teams back on Earth. But there's also an uncomfortable aspect to the shorter flight plan.
That aspect has to do with the Russian-made emergency pressure suits that crew members wear for launch aboard the Soyuz spacecraft. In the past, spacefliers put on the suits several hours before launch, and wore them for about three hours in flight ? long enough to perform the early rocket maneuvers. Then they took off the suits and put them away until docking, two days later. During most of the trip, the travelers could stretch out in the orbital module, a roomier area of the Soyuz spacecraft.
The situation is different for NASA astronaut Chris Cassidy and Russian cosmonauts Alexander Misurkin and Pavel Vinogradov, the newest crew members to head for the space station. Their trip is taking six hours rather than two days, thanks to a more exacting strategy for orbital navigation. The Soyuz launch from Russia's Baikonur Cosmodrome in Kazakhstan is scheduled for 4:43 p.m. ET, and arrival at the station is set for 10:31 p.m. ET.
Mike Suffredini, NASA's space station manager, said the flight plan has the benefit of reducing the "amount of time the crew has to spend in a small environment before they get to the ISS." But that six-hour trip will be more intense.?
Long stretch in the suits
The trio will be wearing their Sokol pressure suits as an essential safety measure, to ensure against the kind of catastrophe that killed three unprotected cosmonauts in 1971 when their cabin suffered an air leak. But the suits are notoriously uncomfortable: They're designed?to fit snugly into the tight crew seats, where knees are shoved halfway up to the chest. Arm mobility is restricted to being able to hold a stick to poke critical controls. Oxygen is fed into the suits via short hoses from a nearby console.
It takes hours to remove the suits and clean them, and at least an hour to put them back on and verify pressurization. There's not time for all that during a six-hour trip. As a result, the crew members will have to wear the suits for a much longer period that begins before launch and doesn't end until after docking.
"They are definitely going to have to go to a very tolerant mental system to do this," one former NASA astronaut told NBC News. The spaceflier, who has experience with Soyuz hardware and the Sokol spacesuit, spoke on condition of anonymity because he wasn't authorized to speak out publicly.
"My first thought was, 'Oh my God, how will they do this!!!" the astronaut said in an email. "If they let the confined/claustrophobic feeling in, it can escalate quickly. If they do not get excellent cooling, which is hard to get, curled up in the seat, it could be very bad. At best this will be terribly uncomfortable to say the least, and I would expect worse, especially given that Cassidy is pretty tall. ... My personal thinking is that this is going too far and even if they get through it this time, I would not think it reasonable as a general technique."
Not 'a big deal'
Cassidy told CollectSpace's Robert Pearlman in an interview that he could tolerate the trip.
"I'm a little bit taller than is comfortably seated in the Soyuz? Cassidy acknowledged, but he said he and his crewmates planned to ease out of their seats and straighten their legs while continuing to wear their spacesuits. "After a couple of hours strapped into that seat tightly, it is really, really nice to stretch your legs out," he explained.
Several retired astronauts seconded Cassidy's view.
"I don't really remember suit comfort being a big deal on my flight," Ed Lu, who was the first American to ride a Soyuz to the space station after the 2003 Columbia disaster, told NBC News via email. "We were out of our suits after 2 revs [revolutions], so what we are talking about here is just an additional 2 revs."
Leroy Chiao, who rode a Soyuz to orbit and back in 2004, agreed in an email: ?While the position one is required to be in for being strapped in the seat is not comfortable, I would opt for day-1 rendezvous. Once in orbit, the crew can loosen their straps a bit and move their legs a little. Shifting around helps relieve some of the discomfort."
It?s not just a matter of NASA employees loyally proclaiming their agreement. Private spaceflight participant Greg Olsen, who took his Soyuz trip in 2005, voiced a similar view in an email: ?Strictly speaking for myself, I would have been willing to keep the Sokol suit on for a 10-hour period if we docked at the station in that time. It would be more uncomfortable, but not unbearable, to do this.?
Space toiletry
Cassidy told CollectSpace that the Russians found a way for crew members to relieve themselves while still inside the suits. "We wind up being in the vehicle for a very, very long time, and people just need to use the toilet eventually," he said, "so we'll open the hatch and have access to the [orbital module] and be allowed to take our suits not completely off, but enough to do any business we need to take care of."
The nature of this "relief tube" remains obscure. Although cosmonauts are often photographed posing in front of their transfer bus for a re-enactment of Soviet space pioneer Yuri Gagarin's "peeing on the tires" ceremony, it's hard to see how they are actually attaining access to allow for urination. Demonstration videos of cosmonauts donning Sokol suits in orbit show clear views of the crotch area, and no openings are visible in the appropriate anatomical regions.
Olsen described the only available method for such relief that he ever was offered. "We all wear 'Huggie' diapers and most have peed at least once shortly after launch,? he said. "The Russians give everyone enemas, so that's not an issue, even for the two-day flight, in most cases."
Perhaps the long stretch in a spacesuit will bring the full truth to light: How do you get relief in orbit?
More about the Soyuz mission:
NBC News space analyst James Oberg spent 22 years at NASA Mission Control, where he carried the title of Rendezvous Guidance and Procedures Officer?? RGPO, pronounced "Arr-Jeep-O." In that capacity he sat in the center of Mission Control's front row, down in the legendary "trench" of space maneuvering specialists.
?
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Mar. 27, 2013 ? An international team of scientists led by the University of Leicester has found new evidence that links faster 'biological' ageing to the risk of developing several age-related diseases -- including heart disease, multiple sclerosis and various cancers.
The study involved scientists in 14 centres across 8 countries, working as part of the ENGAGE Consortium (list of research teams is give below). The research is published online today (27th March) in the journal Nature Genetics.
The project studied a feature of chromosomes called telomeres. Telomeres sit on the end of our chromosomes -- the strands of DNA stored in the nucleus of cells. The telomeres shorten each time a cell divides to make new cells, until they reach a critical short length and the cells enter an inactive state and then die. Therefore telomeres shorten as an individual gets older. But, individuals are born with different telomere lengths and the rate at which they subsequently shorten can also vary. The speed with which telomeres wear down is a measure of 'biological ageing'.
Professor Nilesh Samani, British Heart Foundation Professor of Cardiology at the University of Leicester and Director of the National Institute for Health Research (NIHR) Leicester Cardiovascular Biomedical Research Unit, who led the project said: "Although heart disease and cancers are more common as one gets older, not everyone gets them -- and some people get them at an earlier age. It has been suspected that the occurrence of these diseases may in part be related to some people "biologically" ageing more quickly than others."
The research team measured telomere lengths in over 48,000 individuals and looked at their DNA and identified seven genetic variants that were associated with telomere length. They then asked the question whether these genetic variants also affected risk of various diseases. As DNA cannot be changed by lifestyle or environmental factors, an association of these genetic variants which affect telomere length with a disease also would suggest a causal link between telomere length and that disease.
The scientists found that the variants were indeed linked to risk of several types of cancers including colorectal cancer as well as diseases like multiple sclerosis and celiac disease. Most interestingly, the authors found that in aggregate the seven variants also associated with risk of coronary artery disease which can lead to heart attacks.
Professor Samani added: "These are really exciting findings. We had previous evidence that shorter telomere lengths are associated with increased risk of coronary artery disease but were not sure whether this association was causal or not. This research strongly suggests that biological ageing plays an important role in causing coronary artery disease, the commonest cause of death in the world. This provides a novel way of looking at the disease and at least partly explains why some patients develop it early and others don't develop it at all even if they carry other risk factors."
Dr Veryan Codd, Senior Research Associate at the University of Leicester who co-ordinated the study and carried out the majority of the telomere length measurements said: "The findings open of the possibility that manipulating telomere length could have health benefits. While there is a long way to go before any clinical application, there are data in experimental models where lengthening telomere length has been shown to retard and in some situations reverse age-related changes in several organs."
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/i6UmrgokBGg/130327133339.htm
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Construction of more than 50 new hangars at the DeKalb-Peachtree Airport is underway, the airport director says.
PDK Director Mike Van Wie spoke to the Buckhead Business Association on March 28. He said the project cost more than the original $5 million budget because of federal environmental regulations. Total construction costs will be around $8.3 million, he said.
?Broke ground on the hangar project last week,? Van Wie said.
Van Wie said there will be an official groundbreaking ceremony in April.
During his remarks, Van Wie talked about the economic benefits of general aviation. PDK provides general aviation services, meaning it does not handle commercial or freight traffic. The airport is located on Chamblee Tucker Road and is the second busiest airport in Georgia.
?We?re a general aviation reliever airport,? Van Wie said. ?That reliever designation is important to us. We relieve Hartsfield of the business jets, the Cessna 172s, the prop planes. That reliever status qualifies us for a separate pool of federal money that?s available for capital improvement.?
He said the airport brings in $39.9 million in tax revenue to DeKalb County and traffic at the airport creates 1,834 jobs.
Van Wie said the airport has felt little impact from the sequestration, a series of automatic federal budget cuts that began in March. He said PDK air traffic controllers are federal employees while other Georgia airports use contractors for those jobs.
While PDK receives federal money for improvement projects and air traffic controllers, Van Wie said the current president isn?t a friend of general aviation. Van Wie talked at length about No Plane No Gain advocacy program, a joint effort of the National Business Aviation Association and the General Aviation Manufacturers Association. The group has taken issue with President Obama?s criticism of corporate jets as unnecessary luxuries.
?The current administration has been beating up general aviation at every opportunity,? Van Wie said. ?The No Plane No Gain program started in defense of our industry.?
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What is Gods will for His children? It is to have abundance and prosperity in every aspect of their lives. How can we be sure about this? First of all it is Gods nature to be good. Moreover, His will and promises are written clearly in the Scriptures--words that have seen centuries of lives transformed through knowing His purposes and desires. So how can I get to the wealth that is reserved for me? Is there a prosperity prayer out there that God will hear and answer?
Wait, before you start reciting every prayer you have ever heard,you need to know that its not so much what you say but why and how you say it. God is not after your words or any offering you might give--He wants your heart. He is eager to see you blessed so there is no need to beg for meager resources to get you by. See the whole world as this overflowing abundance of gifts designed with you in mind. Knowing God's goodness will allow you to trust in His providence for your life.
Now you have abundance and prosperity deposited in your account; how can you withdraw from it? By praying according to His promises as stated in the Bible. Agree with His Word and speak prosperity over your life. There is nothing more effective in bringing about change than divine creative word given full reign in somebody's life. Acknowledge your position as a rightful heir to these promises and watch the power of your prosperity prayer begin to manifest. You can use this prayer as a guide:
Father God, I honor You for who You are to me. You are a holy and mighty God, (Luke 1:49) Nothing is impossible for you. (Jeremiah 32:27) All things on earth you have given for man to enjoy, (Psalm 115:16; Jeremiah 27:5) You want only the best for me. (Matthew 7:11; Luke 11:13) It is Your desire to prosper me (Proverbs 28:35) All because You love me. (Jeremiah 31:3; John 1:17; Romans 8:31)
I enter into Your presence bringing with me your promises. You are God and there is no deceit or failure in what You have uttered. (Titus 1:2) When there is no way, I trust You will make one for me. (Joshua 2:10). You give me the wisdom and strength to create wealth, (Deuteronomy 8:18) And You will exceed every goal I set for myself. (Ephesians 3:20)
There is power in Your Word (Hebrews 1:3) It frames the whole world as we know it. (Hebrews 11:3) I agree and speak out Your Word, I trust that it will be as You said. Thank You Father, Your goodness and love surrounds me. I bless Your Name, Amen.
It is vital that you do not entertain negative energy that is bound to come against you one way or another. Combat this by thinking of all the things that are good in your life and start giving thanks for them"no matter how insignificant they may seem at first. There is a peace that will settle in your heart as you do so.
Pray this prosperity prayer whenever you can. It is not a formula or a magic charm to get your prosperity. This prayer serves to remind you of the abundant blessings coming your way, thus strengthening your faith. Use other scriptural verses that you feel a connection to you to. What is important is that you understand that you and your household are title holders to the divine prosperity" and its time to claim it today.
About the Author
Zoe Smith recognizes abundance and prosperity in her life. Learn ways to develop your Prosperity Prayer today.
Read more articles of intrest?
Source: http://www.todayswriting.com/19859/Prosperity-Prayer-Any-Man-Woman-And-Child-Can-Use/
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Source: http://beattiesbookblog.blogspot.com/2013/03/how-to-write-screenplay-7-starting-tips.html
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Mar. 26, 2013 ? Supernovae were always thought to occur in two main varieties. But a team of astronomers including Carnegie's Wendy Freedman, Mark Phillips and Eric Persson is reporting the discovery of a new type of supernova called Type Iax.
This research has been accepted for publication in The Astrophysical Journal.
Previously, supernovae were divided into either core-collapse or Type Ia categories. Core-collapse supernovae are the explosion of a star about 10 to 100 times as massive as our sun. Type Ia supernovae are the complete disruption of a tiny white dwarf.
This new type, Iax, is fainter and less energetic than Type Ia. Although both types come from exploding white dwarfs, Type Iax supernovas may not completely destroy the white dwarf. "A Type Iax supernova is essentially a mini supernova," says lead author Ryan Foley, Clay Fellow at the Harvard-Smithsonian Center for Astrophysics (CfA). "It's the runt of the supernova litter."
The research team--which also included Max Stritzinger, formerly of Carnegie--identified 25 examples of the new type of supernova. None of them appeared in elliptical galaxies, which are filled with old stars. This suggests that Type Iax supernovas come from young star systems.
Based on a variety of observational data, the team concluded that a Type Iax supernova comes from a binary star system containing a white dwarf and a companion star that has lost its outer hydrogen, leaving it helium dominated. The white dwarf collects helium from the normal star.
Researchers aren't sure what triggers a Type Iax. It's possible that the outer helium layer ignites first, sending a shock wave into the white dwarf. Alternatively, the white dwarf might ignite first due to the influence of the overlying helium shell.
Either way, it appears that in many cases the white dwarf survives the explosion, unlike in a Type Ia supernova where the white dwarf is completely destroyed.
The team calculates that Type Iax supernovae are about a third as common as Type Ia supernovae. The reason so few have been detected is that the faintest are only one-hundredth as bright as a Type Ia supernova.
"The closer we look, the more ways we find for stars to explode," Phillips said.
The Large Synoptic Survey Telescope could discover thousands of Type Iax supernovas over its lifetime.
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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/zVYa_cE92VM/130326133337.htm
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T-Mobile's UnCarrier announcement event is taking place a little later today, but some bits of news have started to leak out ahead of time. First was the BlackBerry Z10, and now comes an LTE mobile hotspot, the Sonic 2.0. It's T-mo's first LTE mifi and can feed data to up to eight devices at a time. Not only that, it's compatible with both Mac OSX 10.8 and Windows 8, plus Microsofties get the added benefit of compatibility with the Win8 Carrier application so users can easily access real-time data usage info for every connected gadget. As for the hardware, the Sonic 2.0 has a 1.77-inch color LCD on the front, a 3,000 mAh battery, 802.11 b/g/n WiFi and quadband LTE and 3G radios on board. There's also a MicroSD slot for simple file sharing of up to 32GB cards. It'll be available by the end of the month, though we don't yet know how much it'll cost. Guess you'll have to tune into our liveblog to find out.
Filed under: Wireless, Internet, Mobile
Via: Laptop Mag
Source: T-Mobile
Source: http://www.engadget.com/2013/03/26/t-mobiles-sonic-2-0-mifi-lte/
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At GDC 2013 Sony has decided to focus on its relationships with indie developers, revealing free-to-play PC shooter Blacklight: Retribution and episodic adventure Primal Carnage: Genesis are coming to the PlayStation 4. That makes three self-published games destined for Sony's next-gen console, including Jonathan Blow's The Witness. Blacklight: Retribution is also making use of Sony's Pub Fund for financial and marketing support, the first game on the platform to do so. Sony hasn't forgotten about its existing platforms however, also announcing Spelunky and Divekick for PS3 and Vita, Metrico for Vita, and the handheld debut of Limbo on Vita later this year. Check after the break for a press release that details the announcements, plus trailers for several of the new games.
Via: Joystiq
Source: PlayStation.Blog
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/44A8Wapebsk/
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