Scientists have confirmed the discovery of the first-ever, two-headed bull shark.
The study, led by Michigan State University and appearing in the Journal of Fish Biology, confirmed the specimen, found in the Gulf of Mexico April 7, 2011, was a single shark with two heads, rather than conjoined twins.
There have been other species of sharks, such as blue sharks and tope sharks, born with two heads. This is the first record of dicephalia in a bull shark, said Michael Wagner, MSU assistant professor of fisheries and wildlife, who confirmed the discovery with colleagues at the Florida Keys Community College.
"This is certainly one of those interesting and rarely detected phenomena," Wagner said. "It's good that we have this documented as part of the world's natural history, but we'd certainly have to find many more before we could draw any conclusions about what caused this."
The difficulty of finding such oddities is due, in part, to creatures with abnormalities dying shortly after birth. In this instance, a fisherman found the two-headed shark when he opened the uterus of an adult shark. The two-headed shark died shortly thereafter and had little, if any, chance to survive in the wild, Wagner added.
"You'll see many more cases of two-headed lizards and snakes," he said. "That's because those organisms are often bred in captivity, and the breeders are more likely to observe the anomalies."
The shark was brought to the marine science department at Florida Keys Community College. From there, it was transported to Michigan State's campus for further examination.
Wagner and his team were able to detail the discovery with magnetic resonance imaging. Without damaging the unique specimen, the MRIs revealed two distinct heads, hearts and stomachs with the remainder of the body joining together in back half of the animal to form a single tail.
As part of the published brief, Wagner noted that some may want to attribute the deformed shark to exposure to pollutants.
"Given the timing of the shark's discovery with the Deepwater Horizon oil spill, I could see how some people may want to jump to conclusions," Wagner said. "Making that leap is unwarranted. We simply have no evidence to support that cause or any other."
###
Michigan State University: http://www.newsroom.msu.edu
Thanks to Michigan State University for this article.
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I was a new mom at 36, and there was a lot about motherhood that terrified me. I had no experience with infants, nor did my husband,? Michael. As happy as we were to be expecting, I was filled with fear and trepidation. How on earth would I know what to do?
So it was revelatory to discover that holding my new daughter, Gillian, was like being home.
In my arms her soft, solid warmth still felt a part of me, part of my body. Over the first few weeks the power of my love grew such that nothing could? ever pry her out of my arms. I know this. I knew it once, anyway.
On the morning after Thanksgiving, 1998, Gillian and I were alone in the quiet house. She woke early as 10-week-olds do and smiled as I entered the room.
After our blissful morning cuddle, off we went, toward the stairs, ready to take on the day. Gillian was cooing in my arms and I was thinking about the leftovers and festive clutter needing my attention down in the kitchen.
And just at the top of the stairs ? an overconfident step, slightly off balance, a moment?s distraction. My feet went flying, my hands grasping for the handrails in frantic reflex and instantly, shockingly, Gillian?s soft weight left my hold.
My vision was filled with her face, contorted in surprise but no fear ? she didn?t yet know fear ? floating down the stairway in front of me.
I had slipped at the very top of the stairs, a 14-step flight. As she flew down she looked up at me, her mouth an ?O? and her eyebrows as far up as they could go, all the long way down. As I crashed down the stairs myself, clumsily and painfully, unfathomable thoughts crashed through my brain.
How? How could I ever have let go?
Our child would never grow up, Michael would never forgive me, the pain would be eternal.
I?d wrecked our family forever.
And then she landed. Feet first, face down, her tummy hit the edge of the bottom step as her head clocked the wall, right at the sharp edge of the wooden molding. I frantically finished my own descent, holding my breath and hearing only silence.
And then she cried. Somehow I managed to call 911 and somehow I got Gillian, still wailing, into her bucket-shaped car seat and made my way to the street. The ambulance finally came to take us away.
The questions began immediately. What happened? they asked. Is this your first child? Does she cry a lot? How are you feeling? Have you been sleeping well? Have you been sad?
I understood what they were looking for, but it felt appropriate to be judged and found wanting. Clearly, I thought, I?m unfit for this job. It?s wrong to trust me to take care of my own baby.
Gillian was fine. And forgetful, and forgiving. I wasn?t. Michael carpeted the stair steps and covered me with love and unstinting support. He never wavers from his affirmation that, yes, accidents happen and, yes, this was indeed an accident.
I was not so easily convinced.
The shame of having dropped my baby was ? is ? palpable. You what? You dropped your baby down the stairs? Other mothers can?t fathom such a thing. Of course not. Neither could I, before it happened to me.
We so often hear of tragedy ? a hot car, an unlocked pool gate, the limits of a rear-view mirror ? caused by devoted parents or caregivers. I?m more sympathetic because I think I understand a little bit of the dark shape of a life burdened with guilt beyond repair.
For those brief moments, as my daughter flew dangerously down a long, long flight of stairs, I was there, thinking I had killed my child. And I will never forget.
The Christmas pictures from that year show my wrist brace from my own injury, clear evidence of my carelessness. I walk down those stairs every day and shudder a little, and thank providence once again that we were lucky.
It took a long time but I eventually started to trust myself to keep my baby safe. Our second baby was born two years later, and we managed to get her through her toddler years unscathed. Yet I never felt fully relieved of the guilt until Gillian herself could understand the story and forgive me, and promise me she doesn?t remember a thing.
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Sunday Highlights:Apple inquires indoor location company WifiSLAM, according to the WSJ - more from 9 to 5 Mac, AppleInsider, and Electronista; iMore reports that Apple quickly rolled out a security fix for the password reset vulnerability; BareFeats compares a new Thunderbolt enclosure to the fastest USB 3.0 one, with surprising results; Australia inquiry of Apple, Microsoft, Adobe, others over higher prices in Oz than in other countries; Apple explains high iTunes prices, such as AC/DC's Back In Black being 70% more than in the US, is due to content owners, additional reports in our Apple/Macintosh section; will an iPhone 5S, a "slightly improved" iPhone do anything to quell Apple critics?; Europe scrutinizing Apple's "iPhone sales deals with carriers" for potential antitrust violations; carriers say contracts are "too strict"; former Apple CEO, John Sculley, thinks Jony Ive has the right stuff to notice when the "next big thing" comes along; apparently the Yontoo trojan is slamming Mac users; survey says Apple leading cloud storage wars but Dropbox is hot on their heels; new security measures for iCloud as Apple introduces 2-step authentication, here's how to set it up; Mactuts+ shows how to create PDFs that have fillable forms; iPod touch devices are being used in more and more retail establishments like JC Penney, Urban Outfitters by sales staff in place of cash registers; add two more companies to the smartwatch wars, Google, and LG; Apple continues reign atop J.D. Power's smartphone customer satisfaction survey; Nokia's CEO takes interviewer's iPhone, throws it on the floor; here we go! "low-end iPhone" is coming in 2013, will lack Retina display, sport a plastic case, and arrive alongside the rumored iPhone 5S.
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8:15 PM
News
"Anatomy of the Apple ID password reset exploit"?iMore?3/23
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"Apple rolls out two-factor authentication, iForgot service is back up"?SiliconRepublic?3/23
"Apple rolls out fix for password reset security hole, iForgot site back up"?iMore?3/23
"Apple brings password page back online after fixing security exploit"?The Verge?3/23
"Apple pulls iForgot password recovery system over security bug"?The Register?3/22
"Apple Updates XProtect to Detect Yontoo Adware"?Intego?3/22
"Apple fights Yontoo Trojan with XProtect update: New XProtect definitions identify Yontoo as 'OSX.AdPlugin.i' and block all but the latest versions of Java."?MacFixIt?3/22
"Apple blocks OS X 'Yontoo' malware that injected ads into websites"?9 to 5 Mac?3/22
"Apple updates XProtect.plist to block Yontoo"?AppleInsider?3/22
"Mac Users Getting Slammed By Yontoo Trojan"?CRN?3/22
"Apple leads, Dropbox gains in cloud storage wars: Your digital entertainment habits help propel Apple to quite the lead over other cloud storage services in the U.S., according to a new survey."?CNET News?3/22
"Apple increases iCloud hacking defences: Apple has introduced two-step authentication for iCloud and other services to beef up security against possibly hacking attacks."?Telegraph?3/22
"Security loophole leaves Apple IDs, passwords vulnerable to easy attack"?Digital Trends?3/22
"Apple Enables Two-Step Verification to Thwart Account Hijacking"?eWeek?3/22
"Two-step verification added to Apple IDs"?USA Today?3/22
"Apple confirms password vulnerability, says it's 'working on a fix'"?The Verge?3/22
"Apple Offers Advanced Security Tool"?Zacks?3/22
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Reviews/How-To/Tips
"Riffstation, an app to help you learn guitar parts by ear"?GigaOM?3/23
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"Review: Yandex 1.5 browser offers a lot of Cyrillic, but not much else"?Macworld?3/23
"Mac Gems: Type2Phone pairs your Mac keyboard with your iOS devices"?Macworld?3/22
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"How to Build a Multilingual Site via Wordpress Plugins"?Foliovision?3/22
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"Setting DHCP Reservations on Your AirPort"?Macinstruct?3/22
"MacMost Now 842: Using the Secondary Click"?MacMost?3/22
"Mastering Evernote: Version Control Your Notes With History Feature [OS X Tips]?Cult of Mac?3/22
"Show the total number of messages in Mail mailboxes"?Mac OS X Hints?3/22
"Small Is Beautiful. Less Is More. And 'Done' Is The Mac Todo List App You Can Actually Use"?NoodleMac?3/22
"A Few Words About The #2 Most Useful, Usable, Necessary Mac Utility You Can Buy (it's free, too)"?Mac 360?3/22
"A New And Juicy Way To Manage Color Palettes And Schemes On A Mac"?TeraTalks?3/22
"PassLocker Is The Inexpensive, Easy Way To Secure Logins And Passwords, Mac To iPhone"?Mac 360?3/22
"Just What Every Mac Coder Developer Needs: Yet Another Free Text Editor"?BohemianBoomer?3/22
"A Few Words About The #1 Most Useful, Usable, And Necessary Mac Utility You Can Buy"?Mac 360?3/22
"The Easiest Way Ever For Mac Users To Connect To Remote Servers Right From The Finder"?McSolo?3/22
"How To Fall In Love With A Money Management App That Syncs Up iPhone To Mac"?Mac 360?3/22
Op/Ed
"Looking for the best Google Reader replacement, don't forget the plumbing"?Gravitational Pull?12:18 PM
"DeferredInstall"?Rixstep?6:14 AM
Press Releases
"Ace Slots Machine Casino 2 Brings More Las Vegas Style Slots to the Mac"?prMac?3/23
"Mac Games: Bioshock Infinite, WarCraft Hearthstone Coming This Summer"?FairerPlatform?3/23
"Blizzard's New Gig is a 'Freemium' Card Trading Game"?Tom's Hardware?3/23
"Remo Software Launches PSD Repair Tool for Mac"?prMac?3/22
"Arrival of the Chromebook Pixel forces slight tagline change for Apple's Retina MacBook Pro"?9 to 5 Mac?10:47 AM
"Apple's iPhone 5S could jump-start mobile payments"?MacDailyNews?3/23
"Apple Wants Happy Landings For Fallen Phones: A falling iPhone may no longer result in a cracked screen if one or more of Apple's ideas to protect the device bear fruit."?Sky News?3/23
"The cash register rings its last sale: Stores ditch cash registers, allow sales staff and shoppers to checkout on phones and tablets" ["J.C. Penney, a mid-price department-store chain, said the response by customers has been great since it started rolling out iPod Touch devices late last year in its 1,100 stores. The goal is to have one in the hands of every salesperson by May. The company said that about a quarter of purchases at its stores nationwide now come from an iPod Touch. ... Urban Outfitters had given iPod Touch devices to its sales staff two years ago and the move has been very well received by shoppers, said Calvin Hollinger, the company's chief information officer in his address to investors."]?Associated Press?3/22
"Apple Grabs Top Spot In J.D. Power Customer Satisfaction Study ... Again"?App Advice?3/22
"Apple tops smartphone satisfaction survey for ninth consecutive time"?T3?3/22
"Customer Satisfaction With Smartphones Increases, Apple Ranks Highest For 9th Consecutive Time"?MacPrices?3/22
"Apple and HP top customer experience ratings for computer companies"?Digital Trends?3/22
"Apple & HP Rated Best For Customer Experience [Report]?Cult of Mac?3/22
"Apple adds 'Offers In-App Purchases' App Store warning to freemium apps: iOS store's tweak makes it clearer which apps offer IAP, which may be a boon for parents"?The Guardian?3/22
"Google To Compete With Apple and Samsung On Smart Watch"?Forbes?3/22
"NYT: Apple allegedly squeezing EU operators on iPhone contracts, regulators looking into it"?The Verge?3/22
"Apple under fire from governments in both hemispheres over alleged anti-competitive practices"?9 to 5 Mac?3/22
"15 of the App Store's most bizarre offerings" [Slideshow]?Macworld?3/22
"Apple Agrees to Accept Syria Wargame if It Doesn't Include Syria"?Forbes?3/22
"Apple Yanks 'Sweatshop' Game From The App Store. Oh, The Irony"?ReadWrite?3/22
"Apple bans sweatshop iPad game"?CNET News?3/22
"Chinese Students Are Signing Up For Horrific Loans To Buy Apple Products"?Cult of Mac?3/22
"iPad Hacker Appeals With Cyber Law Expert as New Lawyer"?Mashable?3/22
"Steve Wozniak Talks About Early Apple in Newly Found 1984 Videos"?The Mac Observer?3/22
"iPad-Playing Penguins Try to Nip at Virtual Mouse"?ABCNews?3/22
"Watch Nokia's Stephen Elop Lob Someone Else's iPhone On The Floor, Promise To Replace It"?TechCrunch?3/22
"Elop throws an iPhone on Finnish TV, refuses to answer Lumia 928 questions"?The Verge?3/22
"Kid Fakes Kidnapping to Con an iPad"?PadGadget?3/22
Non-Apple News
"A New Sony Glass Patent Surfaces"?Patent Bolt?9:14 AM
"Senate embraces Internet taxes: Senators vote 75 to 24 to glue an endorsement of Internet sales taxes onto a Democratic budget bill, despite opponents predicting the idea is antibusiness and a 'bureaucratic nightmare.'"?CNET News?3/22
"ARM's new CEO: You'll get no 'glorious new strategy' from me"?The Register?3/22
"Twitter Archive Now Supports 12 More Languages"?PC Magazine?3/22
"Forget Passwords! EyeVerify Knows You by Your Eyes"?PC Magazine?3/22
"Temporary fixes released for Samsung Android lock-screen glitch"?IDG News Service?3/22
"Researchers uncover vSkimmer malware targeting point-of-sale systems: Malware is sold on cybercriminal forums, McAfee researchers say"?IDG News Service?3/22
"Tech hub working on 'Nigeria's next big idea'"?CNN?3/22
"China to create home-grown operating system: China is working with software firm Canonical on an open-source operating system customised for Chinese users."?BBC?3/22
"Female coder is sacked for tweeting picture of men who made 'sexist' dongle jokes at PyCon developer conference"?The Independent?3/22
"At AT&T Stores, No Welcome Mat for BlackBerry"?WSJ.com [Paid Membership Required]?3/22
"BlackBerry CEO Talks Testing Smartphone-Powered Notebooks and Tablets, Will Share More Info In May"?TechCrunch?3/22
"Blackberry boss Thorsten Heins takes bite out of 'outdated' Apple iPhone: Lack of innovation has left iPhone user interface outdated, he says"?The Independent?3/22
"BlackBerry's U.S. Debut Marks Biggest Test of Comeback"?Bloomberg?3/22
"Micron's Revenue Beats Estimates on Higher Chip Shipments"?Bloomberg?3/22
"Vietnamese high school kids can pass Google interview"?The Register?3/22
"Google Opens Universal Analytics Beta To All, Creates A Single Analytics Platform For Tracking Online And Offline Interactions"?TechCrunch?3/22
"Watch Google's Sergey Brin Talk About The Emasculating Smartphone And Google Glass"?TechCrunch?3/22
"Google Drive hit by three outages this week: One of the incidents affected more than 30 percent of user requests to connect to the cloud storage suite"?IDG News Service?3/22
"Google is also working on a smartwatch, following Apple, Samsung"?Los Angeles Times [Paid Membership Required]?3/22
"Kansas City Hosts Hackathon To Develop Apps For Google Fiber"?Forbes?3/22
"LG developing own iWatch and Google Glass-like wearable gizmo"?iDownload Blog?3/22
"Adobe to Australia: Higher pricing is your 'personalised experience'"?ZDNet?3/22
Publications/Podcasts
"iMore show 342: Mobile accomplishments"?iMore?3/23
"Gene Steinberg meets The Loop's Jim Dalrymple, Laptop magazine's Michael Prospero, and Kirk McElhearn, Macworld's 'iTunes Guy,' this week on the Tech Night Owl LIVE!"?The Tech Night Owl LIVE?3/22
"Interview with Janice Stillman of The Old Farmer's Almanac"?Your Mac Life?3/22
"Apple logs patent for 'anti-drop' iPhone technology"?The Scotsman?3/23
"Rumor: First iPhone 5S Components Appear"?Apple Bitch?3/23
"Rumor: Apple to launch cheaper iPhone with plastic casing, non-Retina display this summer"?AppleInsider?3/22
"iPhone 5S, Low-End iPhone With No Retina Display Reportedly Launching This Summer"?BGR?3/22
"When Apple's new iPhones are due"?Fortune?3/22
"Jony Ive Leaves His Mark As Skeuomorphism Concept Vanishes From One App"?App Advice?3/22
"With Apple's Jony Ive leading effort, iOS 7 could have simpler look"?Los Angeles Times [Paid Membership Required]?3/22
"Apple Management Shake-Up Results in Better Collaboration Between Apple Design Teams, New 'Flat' Design for iOS 7"?PadGadget?3/22
"iOS 7 to be flatter, starker, and simpler"?T3?3/22
"Apple's iOS 7 Could Come With Simpler, 'Flat' Design Jony Ive Says"?LAPTOP Magazine?3/22
"Apple iOS Platform Preferred by Enterprises Worldwide: Citrix/The report, which also details trends in dealing with apps and security policies, found iOS is the preferred platform in many vertical industries."?eWeek?3/22
"iPhone 6 Concept: Waterproof iPhone with New Home Button"?GottaBeMobile?3/22
"Photos show alleged Home button, vibrator for iPhone 5S"?Electronista?3/22
"iPhone 5S Update -Everything You Need to Know"?Tapscape?3/22
"Apple warns 'we will reject apps that aren't iPhone 5, Retina ready, use UDID'"?Macworld UK?3/22
"Apple places kill date on apps that use 'UDID' device identifiers"?ZDNet?3/22
"Apple granted four design patents, files for vibrating iPad 5, iBooks Author"?Macworld UK?3/22
"Apple plans iPhone that always falls on its feet"?Telegraph?3/22
"Apple's Next iPhone Could Come With Built-In Drop Protection, Patent Hints"?LAPTOP Magazine?3/22
"Yet more problems said to plague Retina MacBooks: Problems with fans and ghosting on the Retina display, and now claims that users are experiencing 'other significant performance issues'."?Macworld UK?3/22
Price Trackers/Deals
"WarCom: Genesis For iPhone and iPad Is Temporarily Available For Free (Normally $0.99)"?Apple Sliced?3/23
"Centrifeud For iPad Is Free Right Now (Previously $1.99)"?Apple Sliced?3/23
"Fire Escapes For iPhone and iPad Is Free Today (Was $0.99)"?Apple Sliced?3/23
"Fractal Combat For iPhone and iPad Is Temporarily Available For Free (Normally $0.99)"?Apple Sliced?3/22
"Super Goalkeeper For iPhone and iPad Is Free Right Now (Previously $1.99)"?Apple Sliced?3/22
"Save The Pencil For iPhone Is Free Today (Was $1.99)"?Apple Sliced?3/22
"15" MacBook Pro Prices & Sales"?MacPrices?3/22
"13" MacBook Pro Prices & Sales"?MacPrices?3/22
"MacBook Air Prices & Sales"?MacPrices?3/22
"MacBook Pro Prices -13 Inch Models -$1,019 To $2,194 -Best Deals, Reviews & Information"?MacReviewZone?3/22
"MacBook Pro Prices -15 Inch Models -$1,100 to $3,049 -Best Deals, Reviews & Information"?MacReviewZone?3/22
"MacBook Air Prices -$640 To $1,599 -Best Deals, Reviews And Information"?MacReviewZone?3/22
"PadGadget Daily App Deal ? 17 iPad Apps on Sale"?PadGadget?3/22
Deal Brothers Daily Deal: Snapheal for Mac 60% off Today and Tomorrow
Reviews
"Ableton Push review: a dedicated controller for the Live faithful"?Engadget?1:00 PM
"WHICH IS FASTER? Thunderbolt Bus Powered 2.5' or USB 3.0 Bus Powered 2.5' Storage?"?Bare Feats?3/23
"Roku 3 Review: The New Best Streaming Box"?Gizmodo?3/22
"Review: GOAL ZERO's Switch 8 Solar Kit juices your iPhone with sunbeams"?AppleInsider?3/22
"Part Deux: Sapphire Radeon HD 7950 versus other Mac Pro GPUs"?Bare Feats?3/22
"Profectus's iPhone Wallet/Case Is Well Made and Butter Soft"?The Mac Observer?3/22
"iKit NuCharge Battery Case for iPhone 5 Review"?148Apps?3/22
"Review: BodyGuardz ScreenGuardz Pure for iPad Mini"?iSource?3/22
"Review: Moshi Luna keyboard for Mac offers backlit keys, stylish design"?Macworld?3/22
"Video Review DBA CASES Thin Grip Case for iPhone 5"?Run Around Tech?3/22
"Dual-jack Heist may not be Wicked good, but they're pretty good earbuds"?AppleDailyReport?3/22
"Aztaka: These days it seems like the return of the sidescroller. There have been action sidescrollers, stealth sidescrollers, underwater puzzle sidescrollers, and now even an action-RPG sidescroller, Aztaka. Given the large quantity of games to compare it against, does Aztaka bring something new to the table? Does it bring in a new gameplay mechanic, a compelling story, expansive environments, or none of the above? Well, there's only one way to find out. Let's get playing."?Inside Mac Games?3/22
iPad/iPhone/iPod touch Apps
"Ultimate iPad Guide: Note Taking & Idea Apps for Architects"?Architosh?3/23
"Hands on: Apple's Podcasts app loses reel animation, gains playlists/Apple's Podcasts 1.2 for iOS replaces skeuomorphism with iCloud and playlists."?Ars Technica?3/23
"PaperDesk For iPad Is A Powerful, Versatile Note-Taking App We've Come Across In A Long Time"?Redmond Pie?3/23
"Get A Gesture-Based, Predictive Keyboard On Your iPad With Path Input"?AddictiveTips?3/23
"Little Things Forever for iPhone and iPad review"?iMore?3/23
"GarageBand for iOS review: The music creation app that continues to amaze"?CNET Reviews?3/22
"Apple's Podcasts review: New features close the gap, but it's not perfect"?CNET Reviews?3/22
"Review: Apple's Podcasts app catches up with the competition"?GigaOM?3/22
"Hands on: Podcasts 1.2 is the one Apple should have shipped"?Macworld?3/22
"Create & Send Doodles From The iPhone Messages App"?AddictiveTips?3/22
"Thoughts On Mailbox App"?Forbes?3/22
"Over for iOS review: Adding text to your photos is fun with Over"?CNET Reviews?3/22
"Now TV 2.0 for iPad and iPhone review: Movies and Sports on your iOS device"?Macworld UK?3/22
"Addappt opens its contact sync app for iOS to the public with new group and messaging features"?The Next Web?3/22
"Build beautiful slide decks on your iPad with Haiku Deck"?PCWorld?3/22
"Sorry, DNG iPhone app won't let you shoot true raw photos: A new iOS camera app called Digital Negative uses Adobe's DNG format to store uncompressed photos, but it's not the original raw sensor data. Developer Cypress Innovations hopes Apple will open up."?CNET News?3/22
"Moment Camera For iPhone Is A Charming Alternative Snapper With A Beautiful And Clean User Interface"?Redmond Pie?3/22
"Abalone Swims To The App Store, But This Game Is No Wet Fish"?App Advice?3/22
"Review: Karateka for iOS is a beautiful fighting game for the casual player"?Macworld?3/22
"'Le Vamp' Review - This Endless Runner Bites, but That's a Good Thing"?Touch Arcade?3/22
"Plasma-Sky Review: Plasma-Sky is another one of those addictive arcade shooters that is available in the App Store and has the appeal to attract almost anyone to its vibrant and enjoyable gameplay."?148Apps?3/22
"Solitaire Blitz Review"?148Apps?3/22
"Review: Heist and Run ? A Fast-Paced 'Beat The Cops' Racing Game for iOS"?MacTrast?3/22
How-To/Tutorial
"How To speed up Retina MacBook Pro wake from sleep"?iMore?7:42 AM
"How do I print from an iPad: A reader asks Rick Maybury How To go about printing from a 3G iPad"?Telegraph?6:18 AM
"How To accept Game Center friend requests on iPhone and iPad"?iMore?3/23
"How to remove a friend from Game Center on iPhone and iPad"?iMore?3/22
"Apply Live Wallpapers & Scrolling Backgrounds To iPhone Home Screen"?AddictiveTips?3/22
Tips
"Charge Your Phone Faster by Switching to Airplane Mode Before Plugging In"?Lifehacker?3/22
"How Apple invites facile analysis: Conjecture and misunderstanding can trump actual knowledge when it comes to evaluating a company; the hubbub surrounding Apple is a case study."?Los Angeles Times [Free Registration Required]?3/23
"The smartest column about Apple that I've read all week"?Fortune?3/23
"The Macalope Weekly: That's one opinion"?Macworld?3/23
"Apple Anonymous: Tales from behind the Genius Bar"?Fortune?3/23
"For iOS 7, Apple May Dispense with the Leather and Felt"?Techland?3/22
"Why I won't be going back to BlackBerry from iPhone: After using BlackBerry phones for years before switching to an iPhone, I was intrigued to see whether the Z10 could tempt me back. But glitches and a lack of apps left me cold."?CNET Reviews?3/22
"Apple's Wrongheaded, Dangerous Censorship of Satirical Sweatshop for iPad"?Techland?3/22
"Here's One Way Apple Continues to Dominate"?TheStreet?3/22
"Scaling on a Shoestring, Lessons from NewsBlur"?Webmonkey?3/22
"Will Obamacare Tax Your iPhone as a Medical Device?"?CIO?3/22
"The Challenge for Smartphone Makers in 2013"?Tech.pinions?3/22
"Will There Be More Than One New iPhone This Summer?" [Video Report]?Bloomberg?3/22
"Managers: Those iPads coming to work, it's not what you think"?ZDNet?3/22
"Apple: On the art of entering a (corporate) corner/Apple's reconstituted design organization is beginning to work together again."?ZDNet?3/22
GOODYEAR, Ariz. ? Reds third base coach Mark Berry told the team Sunday morning that he has been diagnosed with cancer, but expressed optimism that he will beat it.
?I have cancer,? Berry told reporters after the team meeting. ?I know it sounds bad, the word cancer, but there are plenty of people in this clubhouse that have had it and I know people around the game who have beaten it. My sister had it and beat it. That part hasn?t bothered me.?
The cancer is on his tonsil and two lymph nodes. Berry has been told the cancer is contained to the left side of his neck and has not spread anywhere else. He has yet to decide between surgery or radiation. He will stay with the team in Arizona over the next week before returning to Cincinnati with the team on Saturday. When he returns, he will have further tests to determine the next step of action. His role with the team going forward is undetermined, but he hopes to continue to stay with the team.
Berry said if he chooses to do radiation, it would be a seven-week treatment, five days a week. In that case, he would be with the team at home, but would not travel.
Reds medical director Timothy Kremchek said the cancer was detected relatively early and the prognosis is positive.
?We?re still waiting on one more test to determine exactly what the cancer is, we have a pretty good feeling about what it is,? Berry said. ?Just to put it out there, exactly what it is, we don?t know yet.?
Berry had a surgery on Wednesday in Cincinnati to take out part of his tonsil, and the cancer was diagnosed from that sample. He had previously had two needle biopsies in Scottsdale, with both of those returning negative results for cancer. However, his sister, Michelle Gonzales, had previously had a similar cancer and also had two needle biopsies that didn?t reveal the disease before later confirming it.
Berry, 50, is in his 30th year in the organization as a player, coach or manager. He has been on the team?s big league coaching staff for the last 15 years, the last 10 as the third base coach.
?I don?t want to down play it, but I?m not concerned,? Berry said. ?I?m going to beat it like lots of people in the game I know (have). They did their treatment and moved on. There?s people in the clubhouse right now that went through it. I don?t see any difference.?
Mar. 25, 2013 ? A new analysis has found that genetic alterations in a particular cellular pathway are linked with bladder cancer risk, recurrence, disease progression, and patient survival. Published early online in CANCER, a peer- reviewed journal of the American Cancer Society, the findings could help improve bladder cancer screening and treatment.
Alterations in the regulators of G-protein signaling (RGS) pathway, which is important for various cellular processes, have been implicated in several cancers. Eugene Lee, MD, of the MD Anderson Cancer Center in Houston, and his colleagues sought to determine the role of RGS alterations in bladder cancer risk, recurrence, disease progression, and patient survival. Dr. Lee is currently a fellow of Dr. Ashish M. Kamat. The researchers worked together with Dr. Xifeng Wu's Epidemiology Lab. They studied 803 patients with non-muscle invasive or muscle invasive bladder cancer and 803 healthy individuals.
After evaluating 95 single nucleotide alterations or variants in 17 RGS genes, the investigators identified several that were linked with overall risk of bladder cancer. The strongest association was seen with the rs10759 variant on the RGS4 gene: it was linked with a 0.77-fold reduced risk of overall bladder cancer. The researchers also found that with an increasing number of unfavorable variants, the risk of bladder cancer increased. "Screening for bladder cancer has proven to be difficult on a population level, and our work may be a first step in identifying molecular markers for potential genetic-based screening tests. This will help recognize specific groups at increased risk beyond the existing known risk factors such as smoking and chemical exposure," said Dr. Lee.
Dr. Lee and his team also revealed that in patients with non-muscle invasive bladder cancer, 11 variants were linked with recurrence and 13 variants were linked with progression. Ten were associated with earlier death in patients with muscle invasive bladder cancer; rs2344673 was the most significant, with an average survival of 13.3 months in patients with the variant compared with 81.9 months in patients without it.
In the current era of personalized medicine, an individual's genetic information can provide valuable information on screening, treatment, and surveillance. "Our study provides an initial step in how we can use a patient's genetic makeup to identify those at risk for bladder cancer. Furthermore, we can identify patients who already have a diagnosis of bladder cancer that are at increased risk of worsening of disease or dying from their cancer," said Dr. Lee. "The goal is to find as many genetic alterations that confer risk and create a panel of markers that would aid in diagnosis, treatment, and follow- up."
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The above story is reprinted from materials provided by Wiley.
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Journal Reference:
Eugene K. Lee, Yuanquing Ye, Ashish M. Kamat, Xifeng Wu. Genetic variations in regulator of G-protein signaling (RGS) confer risk of bladder cancer. Cancer, 2013 DOI: 10.1002/cncr.27871
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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Sharanyan SharmaThe exciting news for the small businesses is that the recent E-Commerce revolution has introduced a whole new level playing field offering everyone a fair chance to become an internet business giant very easily enabling everyone to enjoy the big profits.The internet carries the free information flow and everyone?s looking for their necessaries. 8.5110
Online Marketing7
Offline Marketing10
Total Score8.5
The exciting news for the small businesses is that the recent E-Commerce revolution has introduced a whole new level playing field offering everyone a fair chance to become an internet business giant very easily enabling everyone to enjoy the big profits.The internet carries the free information flow and everyone?s looking for their necessaries.
Hey Guys!
Shopping at the city?center?or running errands around your local town lately? While doing these regular chores, if you look closely, you will find huge changes taken place over the recent years.I?m living in Northern Province Vavuniya City, but No matter where you live, I think the little guys- the small stores, independent business owners are all disappearing. At least in my local town, majority of them can?t be found anymore. Most of the local small families running stores offering the homely personal touch are now being all swallowed up by the latest market dominants, the supermarkets and the chain stores which sell almost anything and everything you may need for the day to day life.
It is a really depressing and pathetic scene where numerous out of town retail parks and supermarkets are uprooting the locals and taking their places. Virtually, each major town or city is basically a carbon copy of one other. Anywhere you travel; there is not much diversity or change you can find anymore. In every city or town, it?s the usual brand of coffee shops, all the same cloth stores, the usual chains of garden care companies, DIY or the same restaurants or electrical outlets.These small businesses owners are struggling to survive a losing battle and are loosing their lifeblood as it is being sucked out.
The exciting news for the small businesses is that the recent E-Commerce revolution has introduced a whole new level playing field offering everyone a fair chance to become an internet business giant very easily enabling everyone to enjoy the big profits.The internet carries the free information flow and everyone?s looking for their necessaries.? These are the local folks ? People living in your own area, Your customers with the biggest potentials.
Check out the recent statistics and you?ll get your proof. The trend of researching products and services online is increasing every year as more and more people are getting easy access to high speed internet facilities. Also the smart phone revolution and tablet devices have been a big help. But still, they buy OFFLINE! Grab full advantage of the E-Commerce concept, put your innovative ideas into effect and watch your business flourish. Make this approach, your competitors did and they are doing well.Keep reading and find out how you too can bring out your ?A Game? and someday become an online business giant.
Getting Started Online
Promoting business on the web can be quite overwhelming. This is one of the many reasons why small business owners postpone their advertisement plans over the internet. On the web, there are numerous advertisement techniques available and not having a clear idea might cause trouble deciding where to start from.
Many local businesses dip into the online marketing world and after sometime they give up as the expected results don?t show up.
The internet marketing is efficient and fruitful but it?s not a magic wand which will help you get rich overnight. You know your business by heart, so, now find an easy and simple approach to let the others know.
Not all marketing methods work well for all type of business ventures, but below are some basic things which literally almost any business venture, no matter which sector the venture is related to, can certainly help you to mark your presence on a large scale over the internet without draining your account dry.
Your Online Income Generation Machine ? ?Your Website
You don?t have to create an expensive website with all singing and dancing works of art. The site should be updated regularly and be search engine friendly.Designing a fully functional and yet profitable website is an extremely daunting task. So, small businesses owners usually leave all the designing and technical works to the hired contractors.This sometimes turns out to be an expensive mistake. Website designers are capable of making stunning looking website designs complete using every bell and whistle.
For example, if you were running a car dealership, you would not trust the car mechanics to run your marketing campaigns. He ?may be a damn good car mechanic, but it is almost unlikely that the mechanic would also be an expert authority on marketing. Hand the control of the marketing campaigns over to him and pretty soon you?ll be out of business.Allowing your website designer to run the website for you would put you into similar situations as mentioned above.
Of course, they come with excellent design skills, but they are not experts on marketing in most cases. Only a few website designers completely understand the effective search engine optimization techniques, or how to present compelling sales information or advertisements which effectively pre-sells the products and services you intend to put on the shelves.Believe me; nobody wants a website designer who only focuses on eye catching designs with pretty looking but absolutely pointless gimmicks providing Zero efficiency.Below some tips are presented that will help you run your website with total control and eventually you?ll be running a website providing a healthy profit.
1.? Think straight and be sure about what it is that you really want. You want and need a website working 24/7 with regular earnings. Be clear about exactly what task each web page is expected to accomplish and design them accordingly. Also, in advance, decide what kind of customers your website is trying to attract.
For example, are you interested in showing off your products via an online brochure or do you want to sell those on the website?
?Do you want the webpage to collect the visitor?s contact details or just want the site to let the consumers know your contact details?To keep the customers updated you can go for a blog or newsletter delivery.
2.? Place your offers and make the Buy and contact details clearly visible on the website.? People buy online to save time. So, if you want more online buyers, make the Buy button clearly seen. Make sure that your contact details are visible bright and clearly on each web page, so, the customers can call you if needed.
?Download Your Free Ebook ?
Social media allow you connect with your target audience and have a two-way effective conversation. But it can be easy to forget that not everyone who finds your social media profiles will speak your language, or be able to relate to your region?s latest trends.Social Media Marketing is Secret Weapon for any offline; online business and Brands. Big MNC?s and Small Business owners use social media platform to capture the attention of their target audiences . That?s why?I?ve?created ?special short report about ?Basic E-Commerce Strategies and transform your Business Online using Social media and search Engines. Don?t worry I?m not going to ask you to subscribe my mailing list, but if you like my short report then you can?subscribe my blog to receive Regular updates via email notification.
I hope my short report will help you create some amazing ideas about your business and Brand. Just hit reply to this post and let me know what you thought please.
